lose one's buttons

lose (one's) buttons

To be or become mentally deficient, incompetent, or deranged; to become of unsound mind. My poor grandmother started losing her buttons after she had a stroke on her 84th birthday. I've been so sleep deprived lately that it feels like I'm losing my buttons!
See also: button, lose
Farlex Dictionary of Idioms.

lose one's buttons

see under have all one's buttons.
See also: button, lose
The American Heritage® Dictionary of Idioms by Christine Ammer.
See also:
  • lose (one's) buttons
  • lose (one's) marbles
  • lose your marbles
  • lose all one’s marbles
  • lose marbles
  • lose one’s marbles
  • lose one's marbles
  • lose one's mind
  • lose your mind
  • lose (one's) mind