thrashed adjective tired, worn-down, exhausted, especially as a result of excessive indulgence in hedonistic pleasures; dishevelled US
Johnny Tourist’s idea of a good night out is to get completely thrashed and try to grab hold of any girl who cares to walk past him. — Wayne Anthony, SpanishHighs, p. 88, 1999
She looked really thrashed and kind of droopy from the heroin she was doing. (Quoting Pauly Shore) — SpinMagazine, October 1999