up
it is all up with it is the end or there is no hope for someone or something. informal
2002Guardian The underlying problem is not the science itself, but the fact that the science is telling politicians something they are desperate not to hear: that it's all up with our current model of gung-ho globalisation.
be up on be well informed about a matter or subject.
on the up and up
1 steadily improving. informal
2 honest or sincere. informal, chiefly North American
❷ 2018 Brad ParksCloser than You Know Once the judge sees that the confidential informant isn't on the up and up, he'll have no choice but to toss the warrant.
something is up something unusual or undesirable is afoot or happening. informal
1994Marianne WilliamsonIlluminata It feels as though something is up, as though something significant and big is about to happen.
up against it facing some serious but unspecified difficulty. informal
up and about (or doing) having risen from bed; active.
up for it ready and willing to take part in a particular activity. informal
2003Observer If the chance ever arose to do my singing and play football for Southampton, I'd be well up for it.
up there in the same high category.
2000Apollo Magazine According to Charles Moffett, Co-director of Impressionist and Modern Art at Sotheby's, the painting is 'up there with Dr Gachet', Van Gogh's portrait of his doctor which was sold for $82.5 million in 1990.
up your game improve your performance.
2013Idiot SavantNo Right Turn If Labour wants to continue pretending to lead the opposition, they need to up their game significantly.
up yours! an exclamation expressing contemptuous defiance or rejection of someone. vulgar slang
☞ For other idioms containing up, see the entry for the main word in the idiom (for example, up to scratch at scratch).