1. Totally covered in some liquid or foamy substance, such as soap suds or cream. Everyone in the bachelorette party was busy getting lathered up in fake tan ahead of the night out on the town. Make sure the kids are lathered in sun block before you let them go out on the beach.

2. slang Drunk. The flight attendant was fired for getting lathered in the middle of a flight. Tom kept buying us rounds of drinks, so we stayed pretty lathered up the whole night.