1. vulgar slang Literally, to experience an orgasm in one's pants.

2. vulgar slang To be or become extremely sexually aroused. I creamed my pants when he came onto the stage with his shirt off.

3. vulgar slang By extension, to become overly excited about something. Dude, I know you're hungry, but don't cream your pants, it's just a candy bar. I'm creaming my pants at the thought of going to Paris this summer.