1. Sickly, unwell, or out of sorts, either physically or mentally. You're looking a little off, Jim. Are you feeling all right? That dog on the corner looks a little off. I think we should walk another way home.

2. Somewhat strange, incorrect, inaccurate, or substandard. A: "The rest of your portrait is coming along really well, but the hands look a little off." B: "I know, hands are just so hard to draw!" The gameplay is great, but the graphics on the characters' faces are a little off.

3. Of food, spoiled or rotten. These chicken breasts look a little off—I think we should throw them in the garbage.