1. To bother or inconvenience someone with a question or request about someone or something. I'm sorry to trouble you about this again, but I need your help with a new problem that has cropped up. You should never worry about troubling your teachers or parents about someone who is bullying you in school.

2. To concern oneself with or worry about someone or something. Often used in negative constructions. In this usage, a reflexive pronoun is always used. It's just a minor technical error that should resolve itself—don't trouble yourself about it. I know I need to stop troubling myself about such negative people, but I can't help letting their comments get to me.