1. To twist and undulate the body to propel the body away (from someone or something). I managed to swipe the snake with the broom, sending it across the yard where it promptly slithered away. There's tripwire laid over the entire field, so we'll have to slither away if we want to remain undetected.

2. To walk away (from someone or something) in a sliding motion, especially in a manner that makes others feel uneasy or distrustful. I curtly told the salesman I didn't need any assistance, and I smiled wryly to myself as I watched him slither away to a different customer. I just kept ignoring the sleazebag at the bar until he eventually slithered away.