1. Literally, to look at (one) and smile. The new girl smiled at me, and my heart skipped a beat. I always try to smile at people whenever I'm out and about.

2. To bestow great fortune, happiness, or beneficence upon one. I've been very fortunate in how much life has smiled at me in recent years. I truly believe that God is smiling at our efforts, and it gives me the strength to carry on.