slang Severely intoxicated with drugs or alcohol. We all got pretty looped at the staff party, so no one was feeling particularly productive in the office the next day. Jenny must have taken something at the party, because she looks totally looped.

slang Feeling or showing the effects of taking drugs or alcohol. I only had a couple glasses of wine with my lunch, but I was a bit loopy by the time we left the restaurant. Is it just me, or is Jenny acting a bit loopy? I think she might have taken something at the party. I hate how loopy pain medication makes me, so I try to avoid it.