lack-a-nookie noun a notional disease resulting from a lack of sex US
Peggy said, “And you look like you’re suffering from that rare Hawaiian disease.” “What disease?” Cockeye was concerned. Peggy looked at Cockeye, smiling at him from head to toe. “Lack a nooky, Chump.” — Harry Grey, TheHoods, pp. 103–104, 1952