What's wrong?

What's wrong (with someone or something)?

1. What is going on (with someone or something)? What is the problem (with someone or something)? Hey, what's wrong? You look distressed. What's wrong with this computer? It keeps turning off all on its own. What's wrong with Sarah? She's been in a foul mood all day.
2. Used rhetorically to indicate that someone else is corrupt, immoral, mentally unstable, etc. What on earth is wrong with these people that they could commit such awful crimes? So you just took the money for yourself, even though you knew it would destroy other people's lives? What's wrong with you?
See also: someone, wrong
Farlex Dictionary of Idioms.

What's wrong?

There is something wrong here. What has happened? Mary: Oh, good grief! Bill: What's wrong? Mary: I forgot to feed the cat. Sue (crying): Hello, Sally? Sally: Sue, what's wrong? Sally: Oh, nothing. Tom left me.
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs.
See also:
  • What's wrong (with someone or something)?
  • what's the matter
  • What's the matter (with someone or something)?
  • What's the matter?
  • what's cooking
  • What's cooking?
  • What's good (with you)?
  • What’s really good witcha?
  • What's coming off?
  • What’s coming off?
References in periodicals archive
What's wrong? He didn't answer me." Last night Vasyl's family, of Lucan, Co Dublin, called for the release of his body so he could be buried in the Ukraine.
Certain artists were interspersed through different zones - the Factory photographs of Stephen Shore and Billy Name recur, as do Raymond Pettibon's drawings and Stephen Prina's What's wrong? .