What's with (someone)?

What's with (someone)?

Why is someone so upset or acting in such an unusual way? What's with Jeff? He just screamed at me and stormed out of the room. I wonder what's with Sarah—she's been avoiding me for days now.
Farlex Dictionary of Idioms.

What's with someone or something?

Why is someone or something in that condition?; What's going on with someone or something? Mary: What's with Tom? He looks depressed. Bill: He broke up with Sally. "What's with this stupid coffee maker? It won't get hot!" groused Alice.
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs.

what's with

Also, what's up with; what gives with. What is going on with; tell me about or explain it. For example, What's with all the food they're giving away? or What's up with Lee these days? or What gives with Jack? Why is he so glum? This idiom is also sometimes used as a substitute for how are you or what's wrong, as in Hi, Pam, what's with you? or What gives with you-why are you yelling? [Colloquial; c. 1940]
The American Heritage® Dictionary of Idioms by Christine Ammer.

what’s with somebody?

(American English, spoken) used to ask why somebody is behaving in a strange way: What’s with you? You haven’t said a single word all morning.
Farlex Partner Idioms Dictionary

What’s with someone/something?

interrog. What is wrong with someone or something? What’s with this can opener? It won’t turn.
See also: someone
McGraw-Hill's Dictionary of American Slang and Colloquial Expressions
See also:
  • What's up with (someone)?
  • what's with somebody?
  • What's up?
  • What’s up?
  • what's up
  • What's (someone's) problem?
  • what's your problem?
  • what's eating someone
  • what's eating you
  • What's eating?