the best of friends must part

(even) the best of friends must part

People must inevitably be parted from one another by some means or another. I know it's hard saying goodbye, but even the best of friends must part at some point. I treasure you above all my other friends. But I have to do what's best for my family, and so the best of friends must part.
See also: friend, must, of, part
Farlex Dictionary of Idioms.

(Even) the best of friends must part.

Prov. Even very good friends cannot stay together forever. Child: I don't want Debby to move away. She's my best friend. Mother: Sometimes the best of friends must part, honey, even if they don't want to.
See also: friend, must, of, part
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs.
See also:
  • (even) the best of friends must part
  • say goodbye to (someone or something)
  • (goodbye) till later
  • bye
  • goodbye
  • check you
  • check you later
  • part company
  • part company (with one)
  • part ways (with one)