lose one's mind

lose (one's) mind

1. To become insane or mentally unsound; to become extremely foolish or foolhardy. I'm going to lose my mind if I have to hear that song one more time! I think Jane's grandmother has lost her mind lately. You must have lost your mind if you think that's a good idea!
2. To become exasperated, typically due to attempting a difficult undertaking or dealing with a challenging situation. Often used in the continuous tense. I've been losing my mind trying to juggle work, night school, and the kids. Millie was losing her mind trying to prepare food and manage the front of the house, but thankfully she was able to hire someone to help.
See also: lose, mind
Farlex Dictionary of Idioms.

lose one's mind

Also, lose one's reason. Go crazy, lose one's sanity, as in I thought she'd lost her mind when she said she was going ice-fishing, or That assignment is enough to make me lose my reason. The first expression dates from the late 1500s; the second employs reason in the sense of "unimpaired mental faculties," a usage dating from the late 1300s. Also see under go out of one's mind; have all one's buttons.
See also: lose, mind
The American Heritage® Dictionary of Idioms by Christine Ammer.
See also:
  • lose (one's) mind
  • lose your mind
  • go off (one's) dot
  • go off (one's) rocker
  • lose (one's) buttons
  • lose one's buttons
  • lose your marbles
  • lose all one’s marbles
  • lose marbles
  • lose (one's) marbles
References in periodicals archive
She said the houses are kilometers apart, and one has to be with someone or lose one's mind. I got my mom's point, but it's all in the past now.
The author never really tells us how to get lost, but she offers a few of her own maps, recounts what it means to be lost in the present, to be lost in love, to lose one's mind, the "voluptuous pleasure" in sadness and loss, and the spiritual implications.
"What a waste it is to lose one's mind. Or, not to have a mind is being very wasteful.
The epigraph of Brain Fever is Soren Kierkegaard's statement that "to have faith is precisely to lose one's mind so as to win God."
The country has certainly changed since dan Quayle made his infamous contribution to black institutions: "What a waste it is lose one's mind, or not to have a mind is being very wasteful.