it's all over with (someone)

it's all over with

Something is completely defunct, defeated, closed, finished, or dead. This phrase can refer to something imminent or that has just happened. It's all over with now that the opposing team has a three goal lead. The cancer proved too aggressive; it's all over with for me now.
See also: all, over

it's all over with (someone)

euphemism Someone is about to die or has just died. You guys better get to the hospital—we think it's all over with Aunt Irma.
See also: all, over
Farlex Dictionary of Idioms.

It is all over with someone.

 and It is all over for someone
. Euph. Someone is about to die.; Someone has just died. I am afraid it is all over with Aunt Sarah. Her last surgery did not go well at all. The doctor told us that it was all over for Daddy. We sat for a moment in shock.
See also: all, over
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs.

it's all over with

Something or someone is completely finished, defeated, or dead. The precise meaning of this phrase depends on the context. In This loss means that it's all over with the company, it refers to defeat, whereas in The vet can do no more; it's all over with the dog, it refers to the dog's death, either approaching or actual. Also see all up (with).
See also: all, over
The American Heritage® Dictionary of Idioms by Christine Ammer.
See also:
  • a horse of another
  • a horse of another color
  • a horse of another colour
  • a/the feel of (something)
  • (I) wouldn't (do something) if I were you
  • a straw will show which way the wind blows
  • a crack at (someone or something)
  • all right
  • (you) wanna make something of it?
  • all for the best