cross someone up

cross (one) (up)

To defy, challenge, or frustrate one. Don't cross that guy if you want a job in publishing—he's a celebrated editor. Stephen has crossed me up so many times I just can't trust him anymore.
See also: cross

cross up

1. To deceive or swindle someone. A noun or pronoun can be used between "cross" and "up." Don't cross up that guy if you want a job in publishing—he's a celebrated editor.
2. To confuse or mix up one or more things. I must have crossed up the files—this paperwork doesn't belong in here.
See also: cross, up
Farlex Dictionary of Idioms.

cross someone (up)

and cross up someone
tv. to go against someone; to thwart someone. Don’t cross me up if you know what’s good for you.
See also: cross, someone, up
McGraw-Hill's Dictionary of American Slang and Colloquial Expressions
See also:
  • cross
  • cross (one) (up)
  • cross someone
  • celebrate for an accomplishment
  • GAMMD
  • send (one) (a)round the bend
  • drive (one) up the wall
  • drive someone up the wall
  • drive up the wall
  • drive/send somebody up the wall