American

to have a strong wish to do something and to not allow anything to stop you from doing it.

She's bound and determined to make her career in medical research. (often + to do something)

• cast your lot with someone
• cast your lot with something
• cast your mind back
• cast your net wide
• cast your net wider
• cat and mouse game
• catch 22
• catch as catch can
• catch-as-catch-can
• catch breath
• catch cold
• catch dead to rights
• catch death!
• catch death of cold!
• catch eye
• catch hell
• catch in the act
• catch it
• catch napping
• catch off guard
• catch on the hop
• catch red-handed
• catch sight of
• catch sight of someone
• catch sight of something