take care of take care of (someone/something) 1. to be responsible for someone or something. Our parents spent a lot of time taking care of us when we were young. My mother-in-law fell and could not take care of herself anymore. My wife takes care of paying the bills. 2. to deal with a difficult situation or person. I was forced to take care of all the financial reports, lawyers, and contracts. The principal usually takes care of students who won't follow the rules. Related vocabulary: look after someone/something |