1. if a person is up and down, they are sometimes happy and sometimes sad, usually after something very bad has happened to them.

She's been very up and down since her husband's death.

2. if a situation is up and down, it is sometimes good and successful and sometimes bad and not successful.

Things are up and down for dairy farmers at the moment.

• keep something up to date
• keep sweet
• keep tabs on
• keep tabs on someone
• keep tabs on something
• keep the ball rolling
• keep the home fires burning
• keep the peace
• keep the wolf from the door
• keep time
• keep to
• keep to something
• keep to yourself
• keep track
• keep track of
• keep track of someone
• keep track of something
• keep under hat
• keep under wraps
• keep under your hat
• keep up
• keep up appearances
• keep up something
• keep up to date
• keep up with