| shoot up something shoot up (something) 1. to fire guns, causing great damage to a place. Old western movies usually have a scene where some bad guys ride in and shoot up the town. 2. to take an illegal drug by using a needle. Some athletes are suspected of shooting up steroids to improve their strength. Usage notes: also used in the form shoot someone up - give someone a drug by using a needle: Jim was the first one to shoot me up with heroin. |